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Clinical Studies

5801: The Incidence of Thromboembolic Events in Patients with Antibodies to Heparin-PF4 after Cardiac Bypass

Status: Recruiting

Please Note: The Rare Diseases Clinical Research Network will make every effort to enroll all the patients we can, but we cannot make any guarantees that we will be able to enroll everyone in a particular study who wants to participate.

Summary:

The purpose of this study is to determine how often heart surgery patients who receive heparin develop an immune response (heparin-induced thrombocytopenia) that leads to clots forming in different parts of the body. These clots usually occur in the legs (deep venous thrombosis or DVT) or lungs (pulmonary embolism or PE) or cause heart attacks (myocardial infarction or MI) and strokes.

Target Enrollment:

Expected total enrollment is 800 patients, but the goal enrollment may be later modified.

Patients undergoing cardiac bypass surgery at Duke University Hospital will be screened. All ages are eligible for participation, as well as both genders.

How to Participate:

In order to participate in a study, you must personally contact the study coordinator of any of the participating institutions by phone or by e-mail. Please use the information below to inquire about participation.

  • Duke University Medical Center, Durham NC
    Christine Mette
    Clinical Research Coordinator
    DUMC 3422
    Durham, NC 27710
    Phone: 919-681-9564
    E-mail: mette001@mc.duke.edu

  • Mayo Clinic. Rochester, MN
    Beth Kaping, RN
    St Marys, Joseph 4-221
    Rochester, MN 55905
    Phone: 507-255-7962
    E-mail: kaping.beth@mayo.edu

  • University of Wisconsin, Madison, WI
    Ande Jones
    University of Wisconsin School of Medicine and Public Health
    Box 3244 Clinical Science Center-H4
    600 Highland Ave
    Madison, WI 53792
    Phone: 608-263-0517
    E-mail: anj@medicine.wisc.edu

  • Durham VA Medical Center, Durham, NC
    Lora J. Klein
    Research Coordinator
    Durham VA Medical Center
    508 Fulton Street
    Durham, NC 27705
    Phone: 919-286-6938
    lora.klein@va.gov

You can learn more about this study by joining our contact registry!


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