5510: VCRC Genetic Repository One-Time DNA Study

Status: Recruiting

For Diseases

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss, EGPA), giant cell arteritis (GCA), microscopic polyangiitis (MPA), polyarteritis nodosa (PAN), Takayasu's arteritis (TAK), and Granulomatosis with polyangiitis (Wegener's, GPA).

Background

The purpose of this study is to identify genes that increase the risk of developing vasculitis, a group of severe diseases that feature inflammation of blood vessels. Results of these studies will provide researchers in vasculitis with insight into the causes of these diseases and generate new ideas for diagnostic tests and therapies, and will be of great interest to the larger communities of researchers investigating vasculitis and other autoimmune, inflammatory, and vascular diseases.

About this Study

A total of 1,300 subjects with EGPA, GCA, MPA, PAN, TAK, and GPA will be enrolled in this study. Study subjects will only be seen once for this research study.

For this visit, you will be asked to:

  • Discuss your medical history and disease
  • Give blood (approximately1 tablespoon) for DNA collection

Target Enrollment

To be eligible to participate, you must:

  • Be an individual with a confirmed diagnosis of one of the following:
    • Eosinophilic granulomatosis with polyangiitis (Churg-Strauss, EGPA)
    • Giant Cell Arteritis
    • Microscopic Polyangiitis
    • Polyarteritis nodosa
    • Takayasu's arteritis
    • Granulomatosis with polyangiitis (Wegener's, GPA).

You are not eligible to participate if:

  • You are unwilling to provide blood for DNA collection
  • Are enrolled in another VCRC protocol (because we will already have collected your DNA)

How to participate

In order to participate in a study, you must personally contact the study coordinator of any of the participating institutions by phone or by e-mail. Please use the information below to inquire about participation.

United States

California

  • Cedars-Sinai Medical Center, Los Angeles
    Bonnie Paul
    Study Coordinator
    E-mail: Bonnie.Paul@cshs.org
    Phone: 310-423-2422
  • University of California, San Francisco
    Sharon A. Chung, MD MAS
    E-mail Sharon.chung@ucsf.edu
    Phone: 415-514-1673

Illinois

  • Northwestern University, Chicago
    Mary Carns, MS
    Manager of Clinical Research Programs
    E-mail: m-carns@northwestern.edu
    Phone: 312-503-1137

Kansas

  • University of Kansas Medical Center, Kansas City
    Caitlin McMillian
    Research Business Coordinator
    E-mail: cmcmillian@kumc.edu
    Phone: 913-588-0681

Massachusetts

  • Boston University School of Medicine, Boston
    Naomi Amudala
    Study Coordinator
    E-mail: namudala@bu.edu
    Phone: 617-358-6796

Michigan

  • University of Michigan, Ann Arbor
    Emily Lewis
    Study Coordinator
    Email: eelewis@med.umich.edu
    Phone: 734-936-4009

Minnesota

  • Mayo Clinic College of Medicine, Rochester
    Samantha Hughes
    Study Coordinator
    E-mail: hughes.samantha@mayo.edu
    Phone: 507-266-1026

New York

  • Hospital for Special Surgery, New York
    Annel Fernandez
    Research Assistant
    E-mail: fernandeza@hss.edu
    Phone: 212-774-2123

Ohio

  • Cleveland Clinic, Cleveland
    Elizabeth Kisela
    E-mail: kiselae@ccf.org
    Phone: 216-444-4887

Pennsylvania

  • University of Pittsburgh, Pittsburgh
    Laurie Hope, RN
    Clinical Research Coordinator
    E-mail: hopelk@upmc.edu
    Phone: 412-648-4098

Utah

Canada

Ontario

  • St. Joseph's Healthcare, Hamilton
    Sandra Messier, RCT
    Vascular Medicine Research Coordinator
    E-mail: smessier@stjoes.ca
    Phone: 905-522-1155 Ext. 33260

Turkey

  • Istanbul University, Istanbul
    Sevil Kamali, MD
    Principal Investigator
    E-mail: sevilkamali@hotmail.com
    Phone: 0532 432 12 32