What is expected of you as a participant in the TAPIR trial


To Enroll: Consent to Participate in This Trial

Click the "get started" link on this web site.

We ask that you read and accept the Consent to Participate in Research form.

Physicians' Package

Contact your Doctor

We will provide you with a Physician's Packet for you to download and give to your regular doctor to complete. Please note that an in-person visit with your doctor is not required.

The Physician's Packet will include:

  • information about this trial
  • a medical release form (to send us a copy of your medical records)

Your doctor will fax us back a form along with your medical records if he/she agrees that a trial dose of 5mg or 0mg prednisone per day is appropriate for you. You will be reimbursed a $50 gift card to help offset any charges you may incur for requesting your medical records.

While you are in this trial -

keep seeing your own doctor

Keep seeing your own doctor

You do not need to change or see a new doctor to join this trial.


You will be asked to decrease your prednisone dose down to 5mg per day

Your doctor will recommend a schedule for you to follow in order to decrease your current dose down to 5 mg. This means you will take slightly less prednisone until you are only taking 5mg.

You will be assigned a dose of either 0 or 5 mg per day of prednisone

Once your doctor has returned the Physician Packet and your medical records to the TAPIR trial team, you will be assigned a dose of either 0 or 5 mg per day of prednisone. Your doctor and you will both be notified of which dose (either 5 mg or 0 mg per day of prednisone) you were selected to take.

Your doctor will direct you to keep taking 5mg per day of prednisone daily or decrease your dose to 0mg per day.


Keep an online diary

We will ask you to commit a little time each day to let us know how you are doing. You can do this with our online Prednisone Diary application on your PC, tablet, or with your smart phone.

We will also prompt you to fill out brief surveys/interviews that tell us more about your experiences while in this trial. *Participation in the surveys and interviews is optional.

6 months on study

How long will I be in this trial?

Once you have reached the prednisone dose prescribed by your doctor, you will be in the trial for approximately 6 months.

Will I need to change my dose?

Your prescribed dose while in the trial will be 5 mg or 0 mg per day. Changing your dose from the trial prescribed dose will be a decision between you and your doctor. Additionally, you may also contact our trial coordinator.

If your dose changes from the prescribed trial dose, we ask that you let us know through the MyTAPIR website.

tell us what you think

Tell us what you think

You may be contacted by a member of the TAPIR trial team who will ask you some questions about your participation in this trial.

If you are selected for this follow up interview – someone may contact you at the beginning of the trial (within 2 weeks after we receive the Physician Packet back from your doctor) and again 2 weeks after you have completed the trial (when you have completed 6 months on the trial). These interviews should take no more than 30 minutes and will evaluate the effectiveness of this new trial approach.

If you are selected and agree to participate in one or more of these interviews, you will be compensated for your time with a $25 gift card for each interview.

every experience is valuable

Every experience is valuable to research

Your contribution is invaluable. Every participant experience is important to research of GPA and may provide crucial insight for managing the daily care of GPA patients.

Why it is important for patients to participate in research?


Find out if you are eligible to join >

Read more about what we are studying >

See frequently asked questions.


Ready to join TAPIR?

  • For patients with diagnosed GPA
  • Participate from anywhere - online!
  • Must currently be in remission
  • Continue to see your own doctor

*other conditions may apply. Learn more

Questions Contact our Study Coordinator