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Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium

Grant number: U54 DE035976-01

Principal Investigators

Lead Institution: Children's Hospital of Philadelphia

Diseases Studied

Patient Advocacy Groups

Funding Opportunities

Pilot Study Program

The Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium invites proposals for pilot research projects focused on advancing diagnosis, clinical trial readiness, and management and treatment of syndromic craniosynostosis. This pilot funding opportunity is intended to support early-stage, high-impact projects that generate preliminary data, validate novel concepts, or de-risk innovative approaches with strong potential for downstream translational, clinical, or commercialization impact. Projects supported through this pilot program should align with the broader mission of the ACT Rare Diseases Consortium and complement and/or expand upon the research activities of Clinical Project 1, Clinical Project 2, and Clinical Project 3.

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Funding Statement

The Advancing Craniosynostosis Treatment (ACT) Rare Diseases Consortium is part of the Rare Diseases Clinical Research Network (RDCRN), which is funded by the National Institutes of Health (NIH) and led by the National Center for Advancing Translational Sciences (NCATS) through its Division of Rare Diseases Research Innovation (DRDRI). ACT is funded under grant number U54DE035976 as a collaboration between NCATS, the National Institute of Dental and Craniofacial Research (NIDCR), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). This website is hosted by the network’s Data Management and Coordinating Center at Cincinnati Children’s Hospital Medical Center, which is funded by NCATS and the National Institute of Neurological Disorders and Stroke (NINDS) under grant number TR002818.