The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
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All Diseases > Idiopathic Aortitis
Disease Category: Vasculitis Disorders
A rare disorder characterized by inflammation of the wall of the aorta (the largest artery in the body which transports blood from the heart to the rest of the body). While most forms of aortic inflammation have identified systemic causes, the cause of this form is unknown. Imaging may reveal aortic aneurysms (weakened areas in artery walls) and abnormal aortic wall thickening. Typically, affected individuals are asymptomatic (without symptoms), while others have abdominal or back pain, fever, or pulsing abdominal masses.