The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
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All Diseases > Myasthenia Gravis
Myasthenia Gravis (MG)
Alternative Names: Snowflake Disease
Disease Category: Myasthenia Gravis
A neuromuscular disorder caused by an autoimmune response which blocks or damages acetylcholine receptors in muscles. Affected receptors cannot properly receive nerve signals, impacting voluntary muscle contractions. Generalized muscle weakness and fatigue with prolonged activity are characteristic symptoms, which improve with rest.
Research groups studying this disease
Myasthenia Gravis Rare Disease Network (MGNet)View Disease Definition
8201: Explore MG 2
EXPLORE MG 2 is a natural history study designed to better understand disease characteristics and identify treatment predictive and responsive biomarkers for myasthenia gravis. A total of 300-400 participants with confirmed diagnosis of myasthenia gravis are expected to be enrolled in the study.
Beijing Aili Myasthenia Gravis Care Center
Provides services to myasthenia gravis patients and their families in China through medical, social, and economic support.
Conquer Myasthenia Gravis
Assists individuals affected by myasthenia gravis with programs of support, education, advocacy, and research funding.
European Association of MG Patient Associations
Fosters the exchange of information among MG associations in Europe and ensures that people with MG have a voice in determining their priorities.
Myasthenia Gravis Foundation of America
Aims to find a cure for myasthenia gravis (MG) and closely related disorders, creating a world without MG.