Diseases Studied

The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.

This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email GARDinfo@nih.gov.

All Diseases > Polyarteritis Nodosa

Polyarteritis Nodosa (PAN)

Disease Category: Vasculitis Disorders

A rare, multisystemic disorder characterized by widespread blood vessel inflammation, weakening, and damage, specifically to small- and medium-sized arteries. The kidneys, heart, muscles, intestines, and nervous system are affected, causing high blood pressure, aneurysms (weakened areas in artery walls), blood clots, joint and muscle pain, kidney disease, and tissue damage or necrosis (tissue death) due to blocked blood flow.

Research groups studying this disease

Vasculitis Disorders
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Vasculitis Clinical Research Consortium (VCRC)

View Disease Definition
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