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All Diseases > Severe Combined Immunodeficiency
Severe Combined Immunodeficiency (SCID)
Alternative Names: Bubble Boy Syndrome
Disease Category: Primary Immune Deficiency Disorders
A severe form of primary immune deficiency characterized by extreme weakness or absence of immune system function, manifesting at birth. A dysfunctional immune system is unable to properly defend the body from bacteria, fungi, or viruses, resulting in recurrent, persistent, sometimes life-threatening infections. Common symptoms include chronic diarrhea, failure to thrive (feeding or growth problems), weakness, pneumonia, skin rashes, and oral thrush (a fungal mouth infection).
Research groups studying this disease
Primary Immune Deficiency Disorders
Primary Immune Deficiency Treatment Consortium (PIDTC)View Disease Definition
6901: A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders
6907: Severe Combined Immune Deficiency: Prospective and Longitudinal Study of Genotypes, Management and Outcomes
C-SIDE: Conditioning SCID Infants Diagnosed Early
Immune Deficiency Foundation
Improves the diagnosis, treatment, and quality of life of people affected by primary immunodeficiency.
Jeffrey Modell Foundation
Works to improve treatment, diagnosis, and find a cure for primary immunodeficiency through research, education, support, advocacy, awareness, and newborn screening.
SCID Angels for Life
Increases awareness and provides support for those affected by severe combined immune deficiency (SCID).