Diseases Studied

The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.

This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email GARDinfo@nih.gov.

All Diseases > Chronic Granulomatous Disease

Chronic Granulomatous Disease (CGD)

Disease Category: Primary Immune Deficiency Disorders

An inherited disorder characterized by a weakened immune system that cannot properly protect the body from viruses, fungi, or bacteria. This results in recurrent, persistent, sometimes life-threatening infections. Common symptoms include pneumonia, granulomas (small areas of tissue inflammation) especially in the gastrointestinal and genitourinary tracts, diarrhea, abscesses (pus-filled pockets), and infections of the liver, lymph nodes, and skin.

Research groups studying this disease

Primary Immune Deficiency Disorders
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Primary Immune Deficiency Treatment Consortium (PIDTC)

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Advocates for patients and carriers with chronic granulomatous disease (CGD).

Improves the diagnosis, treatment, and quality of life of people affected by primary immunodeficiency.

Works to improve treatment, diagnosis, and find a cure for primary immunodeficiency through research, education, support, advocacy, awareness, and newborn screening.