The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
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All Diseases > Cryoglobulinemic Vasculitis
Disease Category: Vasculitis Disorders
A rare, autoimmune disorder in which a person's own body attacks itself via antibodies (immune defense proteins) in the blood that form abnormal protein complexes that thicken and clump together when exposed to cold temperatures. This process restricts blood flow to joints, muscles, and organs and causes blood vessel inflammation. Symptoms include joint pain, muscle weakness, purplish skin lesions, skin ulcers, hives, and necrosis (tissue death) of the extremities, especially the fingers and toes.
Research groups studying this disease
Vasculitis Clinical Research Consortium (VCRC)View Disease Definition
Alliance for Cryoglobulinemia
The Alliance For Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and Cryoglobulinemia Ambassadors dedicated to improving the quality of life for people living with cryoglobulinemia.
Lauren Currie Twilight Foundation
We raise awareness of vasculitis, fund research and provide support to people with vasculitis in the UK.
Vasculitis Foundation Canada
Vasculitis Foundation Canada encourages and supports research efforts for the cause and cure for all forms of Vasculitis.
Supports and advances the cause of vasculitis patients, researchers, and healthcare professionals.