The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email GARDinfo@nih.gov.
All Diseases > Cryoglobulinemic Vasculitis
Disease Category: Vasculitis Disorders
A rare, autoimmune disorder in which a person's own body attacks itself via antibodies (immune defense proteins) in the blood that form abnormal protein complexes that thicken and clump together when exposed to cold temperatures. This process restricts blood flow to joints, muscles, and organs and causes blood vessel inflammation. Symptoms include joint pain, muscle weakness, purplish skin lesions, skin ulcers, hives, and necrosis (tissue death) of the extremities, especially the fingers and toes.
Research groups studying this disease
Vasculitis Foundation Canada encourages and supports research efforts for the cause and cure for all forms of Vasculitis.
We raise awareness of vasculitis, fund research and provide support to people with vasculitis in the UK.
Supports and advances the cause of vasculitis patients, researchers, and healthcare professionals.
The Alliance For Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and Cryoglobulinemia Ambassadors dedicated to improving the quality of life for people living with cryoglobulinemia.