Diseases Studied
The Rare Diseases Clinical Research Network is an NIH-funded research network of 21 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email GARDinfo@nih.gov.
All Diseases > Complex lymphatic anomalies
Complex lymphatic anomalies
Disease Category: Vascular Anomalies
Complex lymphatic anomalies (CLA) comprise several high-risk disorders. These disorders can involve the soft tissue, lungs, liver, spleen, intestines, and bones. They can also cause a conduction problem in which the "plumbing system" of the lymphatics is abnormal leading to pleural effusion, pericardial effusion, ascites and edema of the extremities. These conditions can also cause loss of bone and stability leading to infection, paralysis, and death.
Research groups studying this disease
Vascular Anomalies
Advancing Rare Disorders: Vascular mAlformation Research Network with CaNVAS (ARDVARC)