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Diseases Studied

The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.

This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email

All Diseases > Eosinophilic Enteritis

Eosinophilic Enteritis (EoN)

Disease Category: Eosinophilic Gastrointestinal Disorders

A disorder in which eosinophils (white blood cells of the immune system) build up in the intestines. This immune response occurs due to a food or allergen hypersensitivity or unknown other causes. Symptoms can be painful and lifelong. These include heartburn (acid reflux), dyspepsia (abdominal pain), nausea, vomiting, weight loss, bloating, and possibly low albumin levels in the blood.

Research groups studying this disease

Eosinophilic Gastrointestinal Disorders
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Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

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CEGIR is conducting this study because they want to learn more about Eosinophilic Gastrointestinal Diseases (EGIDs). As part of that goal, one area of study will compare how well a patient feels – their symptoms – with what the tissue samples look like under a microscope. The study aims to answer a series of questions, including the following: - What if the tissue looks good, but you are still experiencing symptoms? - What if the symptoms have subsided, but the eosinophil counts haven’t changed?

Supports people affected by eosinophilic gastrointestinal diseases and collaborates with global medical professionals and researchers.

Improves the lives of patients and families affected by eosinophil-associated diseases through education, research, and advocacy.

Supporting those suffering from Eosinophilic Diseases. CURED is dedicated to educate, advocate, spread awareness and committed to raising substantial funding to aid in research. 

Supports and enhances the lives of families living with eosinophilic disorders while educating those around us.

ausEE Inc. Improves the lives of those affected by eosinophilic diseases through providing support, evidence-based information, resources, advocacy and by campaigning to raise awareness and funds for research.