The Rare Diseases Clinical Research Network is an NIH-funded research network of 20 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
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All Diseases > Eosinophilic Granulomatosis with Polyangiitis (EPGA)
Eosinophilic Granulomatosis with Polyangiitis (EPGA) (EGPA)
Alternative Names: Churg-Strauss (CSS)
Disease Category: Vasculitis Disorders
A rare, multisystemic disorder affecting the lungs, kidneys, digestive tract, and extremity nerves. It is characterized by the abnormal clustering of white blood cells called eosinophils in the blood and tissues, vasculitis (blood vessel inflammation), and formation of granulomas (inflamed nodular lesions). Symptoms include allergic reactions, asthma, lung abnormalities, dyspnea (difficulty breathing), coughing, wheezing, malaise (general discomfort), fever, muscle and joint pain, loss of appetite, and weight loss.
Research groups studying this disease
Vasculitis Foundation Canada encourages and supports research efforts for the cause and cure for all forms of Vasculitis.
We raise awareness of vasculitis, fund research and provide support to people with vasculitis in the UK.
Supports and advances the cause of vasculitis patients, researchers, and healthcare professionals.