Diseases Studied
The Rare Diseases Clinical Research Network is an NIH-funded research network of 21 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact them at 1-888-205-2311 or email GARDinfo@nih.gov.
All Diseases > Invasive aspergillosis
Invasive aspergillosis
Disease Category: Fungal Diseases
Invasive aspergillosis (IA) is the most common invasive mold disease. Aspergillus is a genus of mold that comprises a range of species that can cause opportunistic infections in immunocompromised hosts. The pathogen most commonly causes sinus and pulmonary disease but can spread to any part of the body. IA can complicate the course of 1% to 10% of patients in specific immune compromised populations such as those with leukemia and recipients of solid organ or hematopoietic cell transplant recipients. Focusing on this specific genus of mold will provide a more homogeneous group of infections that will allow for documentation of contemporary long-term outcomes for this mold infection.