Diseases Studied
The Rare Diseases Clinical Research Network is an NIH-funded research network of 21 active consortia or research groups working to advance treatment for diseases that are rare. Use the search tools on this page to find the diseases we currently study. You can reach out to the indicated consortia or research groups for more information on those diseases and studies underway.
This network focuses on clinical research and does not generally support clinical care outside of research activities. To learn about other rare diseases, please visit the Genetic and Rare Diseases Information Center (GARD), which is an NIH program that helps the public find reliable information about rare and genetic diseases. Their staff are specialists. Contact their specialists through their web form.
All Diseases > Neuronal ceroid lipofuscinoses (NCLs, Batten diseases): CLN1, CLN2, CLN3, CLN4, CLN5, CLN6, CLN7, CLN8, CLN9, CLN10, CLN11, CLN12, CLN13, CLN14
Neuronal ceroid lipofuscinoses (NCLs, Batten diseases): CLN1, CLN2, CLN3, CLN4, CLN5, CLN6, CLN7, CLN8, CLN9, CLN10, CLN11, CLN12, CLN13, CLN14
Disease Category: Neuronal ceroid lipofuscinoses (NCLs, Batten diseases)
Batten disease is a group of rare, inherited nervous system disorders. It is caused by genetic changes that disrupt the body’s ability to remove cellular waste, leading to a buildup of harmful materials in brain and nerve cells. Over time, this causes progressive neurological decline, including vision loss, seizures, cognitive impairment, motor difficulties, and often shortened lifespan.
Batten Disease is also called neuronal ceroid lipofuscinoses (NCLs). There are 13 recognized NCLs, which vary by age of onset, symptoms, and rate of progression depending on the specific gene involved.
CLN1
CLN2
CLN3
CLN4
CLN5
CLN6
CLN7
CLN8
CLN10
CLN11
CLN12
CLN13
CLN14
Research groups studying this disease
Neuronal ceroid lipofuscinoses (NCLs, Batten diseases)
Batten Disease Clinical Research Consortium (BDCRC)