Contact Information:

• Principal Investigator : Roy Freeman, MBChB
  Professor of Neurology

• Investigator : Christopher Gibbons, MD
  Instructor of Neurology

• Investigator : Istvan Bonyhay, MD, PhD
  Instructor of Neurology

Links:

Beth Israel Deaconess / Harvard Department of Neurology

Center for Autonomic and Peripheral Nerve Disorders: apnervecenter@bidmc.harvard.edu

• Address : Department of Neurology
  Neuroscience Research Center
  4500 San Pablo Road
  Jacksonville, Florida 32224
• For study information contact the research coordinator.

• Principal Investigator : Dr. William Cheshire
• Email : cheshire.william@mayo.edu

• Protocol Coordinator : Alexa Richie, MPH, CCRP
• Phone : 904-953-7839
• Fax : 904-953-6036
• Email : richie.alexa@mayo.edu

About Us

Mayo Clinic Florida

The eight-story Davis Building remains the clinic's largest facility. The Bundy Cafe & Atrium and Mayo Pharmacy are located on the main floor. Other patient facilities include the Mayo Building and the Cannaday Building, which houses the gift shop.

All three buildings are connected by an enclosed walkway and linked to The Inn at Mayo Clinic, a 78-suite hotel. The Courtyard by Marriott, a 146-room hotel, is located near the entrance of the campus.

The Birdsall Medical Research Building has 10 laboratories where scientists investigate neurological diseases such as Alzheimer's. The Griffin Cancer Research Building was completed in 2002 and is the first building on the Jacksonville campus devoted primarily to cancer research.

Mayo Clinic Hospital

Mayo Clinic hospital, which opened in April 2008, integrates inpatient and outpatient services on the Mayo campus in Jacksonville. It has 214 beds and 22 operating rooms and offers care in 20 medical and 15 surgical specialties. It also includes a full-service Emergency Department.

Neurology

Physicians in the Department of Neurology at Mayo Clinic in Florida specialize in diagnosing, treating and researching the hundreds of conditions and diseases that can affect the brain and nervous system. Mayo Clinic neurologists work closely with specialists in neurosurgery, ophthalmology, neuro-oncology, oncology, psychiatry and psychology, pain management, sleep disorders, physical medicine and rehabilitation and many other areas to offer patients comprehensive care.

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Links:

www.mayoclinic.com

www.clinicaltrials.mayo.edu

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List of Publications:

Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I, Cheshire WP, et al. Consensus Statement on the definition of othrostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res. 2011 Apr;21(2):69-72 PMID: 21431947

Rubin DI, Cheshire WP. Evaluation of “Dizziness” in the Neurology Office. Semin Neurol. 2011 Feb;31(1):29-41. Epub 2011 Feb 14. PMID: 21321831

Stomal-Słowińska M, Słowiński J, Lee TK, Uitti RJ, Deen HG, Reimer R, Cheshire WP Jr, Herzog-Bryan G, Wharen RE Jr. Correlation of clinical findings and results of percutaneous balloon compression for patients with trigeminal neuralgia. Clin Neurol Neurosurg. 2011 Jan;113(1):14-21. PMID:20817388

Cheshire WP. Autonomic Assessment in Parkinson’s disease: a measure stride forward. Eur J Neurol. 2010 Feb;17(2):173-4. Epub 2009 Nov 10. No abstract available. PMID: 19906269

• Principal Investigator : Phillip A. Low, MD
  Professor of Neurology

• Investigator : Peter C O’Brien, PhD
  Professor of Biostatistics and Consultant Statistician

Links:

Mayo Clinic: Autonomic Nerve Disorders

• Principal Investigator : David S. Goldstein, MD, PhD
  Chief, Clinical Neurocardiology Section

Links:

National Institute of Neurological Disorders and Stroke / National Institutes of Health

• Principal Investigator : Horacio Kaufmann, MD
  Professor of Neurology, Medicine and Pediatrics

Links:

New York University - Dysautonomia Center

• Principal Investigator : Dr. Susan Perlman
  Clinical Professor of Neurology
  Director, Ataxia Center and HD Center of Excellence
• 300 UCLA Med Plaza, Suite B200
  Los Angeles, CA 90095
• E-mail : sperlman@ucla.edu

• Protocol Coordinator : Tarshia Nulliah
  Clinical Research Coordinator
• Department of Neurology, UCLA
  710 Westwood Plaza, Suite 1150
  Los Angeles, CA 90095
• Office: 310-206-8153
• Fax: 310-206-8720
• E-mail : tnulliah@mednet.ucla.edu

About Us:

Dr. Susan Perlman is a Professor in the Department of Neurology at the David Geffen School of Medicine at UCLA. She is also Director of Ataxia and Neurogenetics Program and Post-polio Program at that school. She has long been the primary investigator for Friedreich's ataxia trials and sits on the Medical Advisory Board of the National Ataxia Foundation.

Dr. Perlman received her B.S. in Biochemistry in 1971 from Cornell University and her MD in 1975 from S.U.N.Y. Stony Brook. She did her Residency in Neurology at UCLA 1976-1979 followed by a two year Muscular Dystrophy Association Fellowship in Neurology also at UCLA.

On May 30, 2008, Dr. Perlman was presented with the Sherman M. Mellinkoff Faculty Award at the Hippocratic Oath ceremony of the graduating class of 2008. The award is considered the highest faculty distinction at the David Geffen School of Medicine.

Links:

UCLA David Geffen School of Medicine Department of Neurology

List of Publications:

1. Lynch DR, Farmer JM, Tsou AY, Perlman S, Subramony SH, Gomez CM, Ashizawa T, Wilmot GR, Wilson RB, Balcer LJ. (2006) Measuring Friedreich ataxia: complementary features of examination and performance measures. Neurology 66:1711-6.
2. Li JL, Hayden MR, Warby SC, Durr A, Morrison PJ, Nance M, Ross CA, Margolis RL, Rosenblatt A, Squitieri F, Frati L, Gómez-Tortosa E, García CA, Suchowersky O, Klimek ML, Trent RJ, McCusker E, Novelletto A, Frontali M, Paulsen JS, Jones R, Ashizawa T, Lazzarini A, Wheeler VC, Prakash R, Xu G, Djoussé L, Mysore JS, Gillis T, Hakky M, Cupples LA, Saint-Hilaire MH, Cha JH, Hersch SM, Penney JB, Harrison MB, Perlman SL, Zanko A, Abramson RK, Lechich AJ, Duckett A, Marder K, Conneally PM, Gusella JF, MacDonald ME, Myers RH. (2006) Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study. BMC Med Genet. 7:71.
3. McMurtray AM, Clark DG, Flood MK, Perlman S, Mendez MF. (2006) Depressive and memory symptoms as presenting features of spinocerebellar ataxia. J Neuropsychiatry Clin Neurosci. 18:420-2.
4. Herman D, Jenssen K, Burnett R, Soragni E, PerlmanSL, Gottesfeld JM (2006) HDAC Inhibitors Reverse Gene Silencing in Friedreich’s Ataxia. Nature Chemical Biology Nat Chem Biol. 2:551-8. Epub 2006 Aug 20. Erratum in: Nat Chem Biol. 2007 3:432.

• Principal Investigator : Dr. Stephanie Lessig, MD
  Department of Neurosciences
• 3350 La Jolla Village Drive (9127)
  La Jolla, CA 92161
• E-mail: slessig@ucsd.edu

• Protocol Coordinator : Deborah Fontaine, NP
  Department of Neurosciences
• 8950 Villa La Jolla, Suite C129
  San Diego, CA 92037
• Office : 858-246-1246
• Fax : 858-622-1012
• E-mail: dfontaine@ucsd.edu

Links:

www.ucsd.edu

neurosciences.ucsd.edu

• Principal Investigator : Sid Gilman MD, FRCP
  William J. Herdman Distinguished University Professor of Neurology, Department of Neurology, University of Michigan
  Director, Michigan Alzheimer’s Disease Center

• Research Coordinator : Arijit Bhaumik, BA
  Clinical Research Coordinator
• Department of Neurology
  Michigan Alzheimer’s Disease Center
  2101 Commonwealth Blvd. Suite D
  Ann Arbor, MI 48105
• Office : 734-936-8281
• Fax : 734-764-6444
• E-mail : arijit@umich.edu

About Us:

MADC Commitment to Memory and Aging Research

For over two decades the Michigan Alzheimer's Disease Center (MADC) has contributed to the expanding knowledge on Alzheimer’s disease and related dementias. Established at the University of Michigan Health System in 1989, the MADC is devoted to enhancing recruitment for memory and aging research, promoting high quality clinical care, and providing current information on Alzheimer's disease and related disorders. In addition to Alzheimer’s disease, the MADC supports research and clinical care in related cognitive disorders including vascular dementia, frontotemporal dementia, Lewy body disease, and dementia associated with Parkinson disease. The research has expanded beyond purely cognitive disorders into areas involving autonomic failure, cerebellar ataxia, and parkinsonian symptoms such as multiple system atrophy. Continued research is critically important to finding a cure and helping the millions of people already affected by these disorders. The MADC supports local, state and national research efforts emphasizing the transition from normal aging to early cognitive impairment, and is taking a lead role in coordinating efforts at the UMHS to explore the emerging role of comorbidities in cognitive disorders.

Links:

The Michigan Alzheimer’s Disease Center

University of Michigan Health System

Department of Neurology

List of Publications:

1. May S, Gilman S, Sowell BB, Thomas RG, Stern MB, Colcher A, Tanner CM, Huang N, Novak P, Reich SG, Jankovic J, Ondo WG, Low PA, Sandroni P, Lipp A, Marshall FJ, Wooten F, Shults CW; North American Multiple System Atrophy Study Group. Potential outcome measure and trial design issues for multiple system atrophy._Mov Disord. 2007 Dec;22(16):2371-7. PMID: 17914727
2. Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, Wood N, Colosimo C, Dϋrr A, Fowler CJ, Kaufmann H, Klockgether T, Lees A, Poewe W, Quinn N, Revesz T, Robertson D, Sandroni P, Seppi K, Vidailhet M. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008; 71:670-676. PMCID: PMC2676993
3. Gilman S, Koeppe RA, Nan B, Wang, C-N, Junck L, Chervin R, Consens F, Bhaumik, A (2009). Cerebral Cortical and Subcortical Cholinergic Deficits in Parkinsonian Syndromes. Neurology.
4. Gilman S, Koeppe RA, Nan B, Wang C-N, Wang X, Junck L, Chervin R, Consens F, Bhaumik A. Cerebral cortical and subcortical cholinergic deficits in parkinsonian syndromes. Neurology 2010; 74: 1416-1423. PMCID: PMC2871002 [2011/5/4]

• Principal Investigator : Steven Vernino, MD PhD
  Professor of Neurology and Neurotherapeutics
• 5323 Harry Hines Blvd
  Dallas, TX 75390-9036
• E-mail : steven.vernino@utsouthwestern.edu

• Investigator : Srikanth Muppidi, MD
  Assistant Professor of Neurology and Neurotherapeutics
• E-mail : srikanth.muppidi@utsouthwestern.edu

• Investigator : Shilpa Chitnis, MD PhD
  Professor of Neurology and Neurotherapeutics
  Movement Disorders Section
• E-mail : shilpa.chitnis@utsouthwestern.edu

• Clinical Research Coordinator : Nina Gorham
• Office : 214-648-9275
• Fax : 214-648-9129
• E-mail : nina.gorham@utsouthwestern.edu

Links:

Institution Main Web Site

Department Web Site

• Principal Investigator : Italo Biaggioni, MD
  Professor of Medicine and Pharmacology
• E-mail : Italo.biaggioni@vanderbilt.edu

• Investigator : Thomas L Davis
  Professor, Neuro-Movement Disorders Division
• E-mail : thomas.l.davis@Vanderbilt.Edu

• Investigator : Christopher M Tolleson, MD
  Instructor, Neuro-Movement Disorders Division
• E-mail : christopher.tolleson@Vanderbilt.Edu

• Investigator : Satish R. Raj, MD
  Assistant Professor of Medicine and Pharmacology
• E-mail : Satish.raj@vanderbilt.edu

• Investigator : André M. Diedrich, MD, PhD
  Professor of Medicine
  Professor of Biomedical Engineering
• E-mail : andre.diedrich@vanderbilt.edu

• Investigator : William D Dupont, MSc, PhD
  Professor of Biostatistics and Preventive Medicine
• E-mail : William.dupont@vanderbilt.edu

• Investigator : Alfredo Gamboa, MD
  Research Assistant Professor
• E-mail : Alfredo.gamboa@vanderbilt.edu

• Investigator : Emily Garland, PhD
  Associate Professor
• E-mail : emily.garland@vanderbilt.edu

• Investigator : Maureen K. Hahn, PhD
  Assistant Professor
• E-mail : Maureen.hahn@vanderbilt.edu

• Investigator : Lynda Lane, MS, RN
  Senior Associate in Medicine
  Administrative Director; Clinical Research Center
• E-mail : Lynda.Lane@Vanderbilt.Edu

• Consortium Project Manager / Site Coordinator : Emily M. Garland, PhD, MSCI
• E-mail : emily.garland@Vanderbilt.Edu
• Office : 615-936-1748

Links:

Vanderbilt University: Autonomic Dysfunction Center Home